Soft computing in case based reasoning
Soft computing in case based reasoning
Inside Case-Based Reasoning
Knowledge Discovery in GENBANK
Proceedings of the 1st International Conference on Intelligent Systems for Molecular Biology
Machine learning in DNA microarray analysis for cancer classification
APBC '03 Proceedings of the First Asia-Pacific bioinformatics conference on Bioinformatics 2003 - Volume 19
Case Generation Using Rough Sets with Fuzzy Representation
IEEE Transactions on Knowledge and Data Engineering
Foundations of Soft Case-Based Reasoning
Foundations of Soft Case-Based Reasoning
Improving classification of microarray data using prototype-based feature selection
ACM SIGKDD Explorations Newsletter
Machine learning in low-level microarray analysis
ACM SIGKDD Explorations Newsletter
Maximum likelihood hebbian learning based Retrieval method for CBR systems
ICCBR'03 Proceedings of the 5th international conference on Case-based reasoning: Research and Development
Using fuzzy patterns for gene selection and data reduction on microarray data
IDEAL'06 Proceedings of the 7th international conference on Intelligent Data Engineering and Automated Learning
Applying GCS networks to fuzzy discretized microarray data for tumour diagnosis
IDEAL'06 Proceedings of the 7th international conference on Intelligent Data Engineering and Automated Learning
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In recent years, machine learning and data mining fields have found a successful application area in the field of DNA microarray technology. Gene expression profiles are composed of thousands of genes at the same time, representing complex relationships between them. One of the well-known constraints specifically related to microarray data is the large number of genes in comparison with the small number of available experiments or cases. In this context, the ability to identify an accurate gene selection strategy is crucial to reduce the generalization error (false positives) of state-of-the-art classification algorithms. This paper presents a reduction algorithm based on the notion of fuzzy gene expression, where similar (co-expressed) genes belonging to different patients are selected in order to construct a supervised prototype-based retrieval model. This technique is employed to implement the retrieval step in our new gene-CBR system. The proposed method is illustrated with the analysis of microarray data belonging to bone marrow cases from 43 adult patients with cancer plus a group of three cases corresponding to healthy persons.