Self-organizing maps
Machine learning in DNA microarray analysis for cancer classification
APBC '03 Proceedings of the First Asia-Pacific bioinformatics conference on Bioinformatics 2003 - Volume 19
Microarray data mining: facing the challenges
ACM SIGKDD Explorations Newsletter
Improving gene selection in microarray data analysis using fuzzy patterns inside a CBR system
ICCBR'05 Proceedings of the 6th international conference on Case-Based Reasoning Research and Development
An automatic diagnosis method for the knee meniscus tears in MR images
Expert Systems with Applications: An International Journal
Hi-index | 0.00 |
Gene expression profiles belonging to DNA microarrays are composed of thousands of genes at the same time, representing the complex relationships between them. In this context, the ability of designing methods capable of overcoming current limitations is crucial to reduce the generalization error of state-of-the-art algorithms. This paper presents the application of a self-organised growing cell structures network in an attempt to cluster biological homogeneous patients. This technique makes use of a previous successful supervised fuzzy pattern algorithm capable of performing DNA microarray data reduction. The proposed model has been tested with microarray data belonging to bone marrow samples from 43 adult patients with cancer plus a group of six cases corresponding to healthy persons. The results of this work demonstrate that classical artificial intelligence techniques can be effectively used for tumour diagnosis working with high-dimensional microarray data.