DNA extraction by XPCR

  • Authors:
  • Giuditta Franco;Cinzia Giagulli;Carlo Laudanna;Vincenzo Manca

  • Affiliations:
  • Department of Computer Science, University of Verona;Section of General Pathology, Department of Pathology, University of Verona;Section of General Pathology, Department of Pathology, University of Verona;Department of Computer Science, University of Verona

  • Venue:
  • DNA'04 Proceedings of the 10th international conference on DNA computing
  • Year:
  • 2004

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Abstract

The extraction of DNA strands including a given sequence of bases is a crucial step in the Adleman-Lipton extract model of DNA computing. In this paper, a special type of PCR is presented with a related algorithm which performs a specified extraction from a given pool of DNA double stranded (shortly dsDNA) molecules. This kind of PCR, called Cross Pairing PCR (shortly XPCR) was tested in several situations, and used in a biotechnological procedure which implements the extraction algorithm.