Solution of a Satisfiability Problem on a Gel-Based DNA Computer

  • Authors:
  • Ravinderjit S. Braich;Cliff Johnson;Paul W. K. Rothemund;Darryl Hwang;Nickolas V. Chelyapov;Leonard M. Adleman

  • Affiliations:
  • -;-;-;-;-;-

  • Venue:
  • DNA '00 Revised Papers from the 6th International Workshop on DNA-Based Computers: DNA Computing
  • Year:
  • 2000

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Abstract

We have succeeded in solving an instance of a 6-variable 11- clause 3-SAT problem on a gel-based DNA computer. Separations were performed using probes covalently bound to polyacrylamide gel. During the entire computation, DNA was retained within a single gel and moved via electrophoresis. The methods used appear to be readily automatable and should be suitable for problems of a significantly larger size.