Aqueous computing with DNA hairpin-based RAM

Authors:
Naoto Takahashi;Atsushi Kameda;Masahito Yamamoto;Azuma Ohuchi
Affiliations:
Graduate School of Engineering, Hokkaido University, Hokkaido, Japan;CREST, Japan Science and Technology Agency (JST), Saitama, Japan;CREST, Japan Science and Technology Agency (JST) and Graduate School of Information Science and Technology, Hokkaido University, Hokkaido, Japan;CREST, Japan Science and Technology Agency (JST) and Graduate School of Information Science and Technology, Hokkaido University, Hokkaido, Japan
Venue:
DNA'04 Proceedings of the 10th international conference on DNA computing
Year:
2004

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Abstract

DNA RAM can eliminate the computational overhead of sequence design because the same RAM can be used for various computations once it is made. In this paper, we report a new method to construct RAM by using the hairpin structure of DNA, and the 4-bit RAM that we actually constructed with this method. We conducted an experiment to distinguish all 16 states of the 4-bit RAM, and another to verify our achievement of a successive writing operation. Finally, we performed aqueous computing with this 4-bit RAM.