VICE: a VIrtual CEll

  • Authors:
  • D. Chiarugi;M. Curti;P. Degano;R. Marangoni

  • Affiliations:
  • Dipartimento di Informatica, Università di Pisa, Pisa, Italy;Dipartimento di Informatica, Università di Pisa, Pisa, Italy;Dipartimento di Informatica, Università di Pisa, Pisa, Italy;Dipartimento di Informatica, Università di Pisa, Pisa, Italy

  • Venue:
  • CMSB'04 Proceedings of the 20 international conference on Computational Methods in Systems Biology
  • Year:
  • 2004

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Abstract

We report on the specification and analysis of VICE, a hypothetical cell with a genome as basic as possible. We used an enhanced version of the π-calculus and a prototype running it to study the behaviour of VICE. The results of our experimentation in silico confirm that our virtual cell “survives” in an optimal environment and shows a behaviour similar to that of real prokaryotes.