Seamless Integration of Biological Applications within a Database Framework
Proceedings of the Seventh International Conference on Intelligent Systems for Molecular Biology
Applying Data Warehouse Concepts to Gene Expression Data Management
BIBE '01 Proceedings of the 2nd IEEE International Symposium on Bioinformatics and Bioengineering
Database management for life sciences research
ACM SIGMOD Record
The integrated microbial genomes (IMG) system: a case study in biological data management
VLDB '05 Proceedings of the 31st international conference on Very large data bases
Scientific data management in the coming decade
ACM SIGMOD Record
Biological data management: research, practice and opportunities
VLDB '04 Proceedings of the Thirtieth international conference on Very large data bases - Volume 30
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Scientific laboratories are rich in data management challenges. This paper describes an end-to-end information management infrastructure for a high throughput proteomics industrial laboratory. A unique feature of the platform is a data and applications integration framework that is employed for the integration of heterogeneous data, applications and processes across the entire laboratory production workflow. We also define a reference architecture for implementing similar solutions organized according to the laboratory data lifecycle phases. Each phase is modeled by a set of workflows integrating programs and databases in sequences of steps and associated communication and data transfers. We discuss the issues associated with each phase, and describe how these issues were approached in the proteomics implementation.