Programming pearls
Journal of Computer and System Sciences - Computational biology 2002
Convex Optimization
An optimal algorithm for maximum-sum segment and its application in bioinformatics
CIAA'03 Proceedings of the 8th international conference on Implementation and application of automata
On the range maximum-sum segment query problem
ISAAC'04 Proceedings of the 15th international conference on Algorithms and Computation
Efficient calculation of interval scores for DNA copy number data analysis
RECOMB'05 Proceedings of the 9th Annual international conference on Research in Computational Molecular Biology
A geometric framework for solving subsequence problems in computational biology efficiently
SCG '07 Proceedings of the twenty-third annual symposium on Computational geometry
ISAAC'07 Proceedings of the 18th international conference on Algorithms and computation
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We consider a generalization of the maximum subsequence problem. Given an array a1,...,an of real numbers, the generalized problem consists in finding an interval [i,j] such that the length and the sum of the subsequence ai,...,aj maximize a given quasiconvex function f. Problems of this type occur, e.g., in bioinformatics. We show that the generalized problem can be solved in time O(n log n). As an example, we show how the so-called multiresolution criteria problem can be solved in time O(n log n).