The program-size complexity of self-assembled squares (extended abstract)
STOC '00 Proceedings of the thirty-second annual ACM symposium on Theory of computing
Running time and program size for self-assembled squares
STOC '01 Proceedings of the thirty-third annual ACM symposium on Theory of computing
Combinatorial optimization problems in self-assembly
STOC '02 Proceedings of the thiry-fourth annual ACM symposium on Theory of computing
Algorithmic self-assembly of dna
Algorithmic self-assembly of dna
On the behavior of tile assembly system at high temperatures
CiE'12 Proceedings of the 8th Turing Centenary conference on Computability in Europe: how the world computes
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Winfree's abstract Tile Assembly Model (aTAM) is a model of molecular self-assembly of DNA complexes known as tiles, which float freely in solution and attach one at a time to a growing "seed" assembly based on specific binding sites on their four sides. We show that there is a polynomial-time algorithm that, given an n ×n square, finds the minimal tile system (i.e., the system with the smallest number of distinct tile types) that uniquely self-assembles the square, answering an open question of Adleman, Cheng, Goel, Huang, Kempe, Moisset de Espanés, and Rothemund (Combinatorial Optimization Problems in Self-Assembly, STOC 2002). Our investigation leading to this algorithm reveals other positive and negative results about the relationship between the size of a tile system and its "temperature" (the binding strength threshold required for a tile to attach)