A Top-r Feature Selection Algorithm for Microarray Gene Expression Data

  • Authors:
  • Alok Sharma;Seiya Imoto;Satoru Miyano

  • Affiliations:
  • University of Tokyo, Tokyo, and University of the South Pacific;University of Tokyo, Tokyo;University of Tokyo, Tokyo

  • Venue:
  • IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
  • Year:
  • 2012

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Abstract

Most of the conventional feature selection algorithms have a drawback whereby a weakly ranked gene that could perform well in terms of classification accuracy with an appropriate subset of genes will be left out of the selection. Considering this shortcoming, we propose a feature selection algorithm in gene expression data analysis of sample classifications. The proposed algorithm first divides genes into subsets, the sizes of which are relatively small (roughly of size h), then selects informative smaller subsets of genes (of size r