Comparing the dimensionality reduction methods in gene expression databases

  • Authors:
  • Helyane Bronoski Borges;Júlio Cesar Nievola

  • Affiliations:
  • UTFPR - Universidade Tecnológica Federal do Paraná, Brazil and PPGIa - Pontifícia Universidade Católica do Paraná (PUCPR), Brazil;PPGIa - Pontifícia Universidade Católica do Paraná (PUCPR), Brazil

  • Venue:
  • Expert Systems with Applications: An International Journal
  • Year:
  • 2012

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Abstract

Dimensionality reduction has been applied in the most different areas, among which the data analysis of gene expression obtained with the microarray approach. The data involved in this problem is challenging for machine learning algorithms due to a small number of samples and a high number of attributes. This paper proposes a preprocessing phase by means of attribute selection and random projection method in microarray data. Experimental results are promising and show that the use of these methods improves the performance of classification algorithms.