Optimal control of bacterial growth

Authors:
G. D'Ans;D. Gottlieb;P. Kokotovic
Affiliations:
IBM Thomas J. Watson Research Center, Yorktown Heights, N.Y. 10598 USA;Department of Plant Pathology and Coordinated Science Laboratory, University of Illinois, Urbana, Illinois 61801 USA;Department of Plant Pathology and Coordinated Science Laboratory, University of Illinois, Urbana, Illinois 61801 USA
Venue:
Automatica (Journal of IFAC)
Year:
1972

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Abstract

A stabilizing feedback control is designed for Haldane-Monod model of microbial growth. The controlled process is optimal in the sense that it approaches the maximum production steady-state from any initial state, while the amount of microorganisms produced in transients is also maximized. Data from a series of experiments are given and used to adjust the model parameters. Satisfactory agreement between experimental and model transients is obtained.