The nature of statistical learning theory
The nature of statistical learning theory
A Tutorial on Support Vector Machines for Pattern Recognition
Data Mining and Knowledge Discovery
MICCAI '98 Proceedings of the First International Conference on Medical Image Computing and Computer-Assisted Intervention
Expert Systems with Applications: An International Journal
Cluster analysis of genome-wide expression data for feature extraction
Expert Systems with Applications: An International Journal
Expert Systems with Applications: An International Journal
18F-FDG PET imaging analysis for computer aided Alzheimer's diagnosis
Information Sciences: an International Journal
Computer aided diagnosis of Alzheimer's disease using component based SVM
Applied Soft Computing
Computer Aided Diagnosis tool for Alzheimer's Disease based on Mann-Whitney-Wilcoxon U-Test
Expert Systems with Applications: An International Journal
Expert Systems with Applications: An International Journal
Expert Systems with Applications: An International Journal
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In this work, SPECT brain images are analyzed automatically in order to determine the effects of acupuncture applied for fighting migraine. For this purpose, two different groups of patients are randomly collected and received verum and sham acupuncture, respectively. Changes in the brain perfusion patterns can be measured quantitatively by dealing with the images in a classification context. A classification scheme consisting of a component-based feature extraction technique in combination with Support Vector Machines allows us to accurately determine the regions of interest (ROIs) where acupuncture produced more intense effects, and whether these effects are correlated with a decrease or an increase of the brain activity. Effects produced by verum and sham acupuncture are studied, and the best method for intensity normalization is discussed. The result is a complete, objective system which can be used for general purposes in the visual assessment of perfusion images.