Facilitating pharmacometric workflow with the metrumrg package for R

Authors:
Timothy T. Bergsma;William Knebel;Jeannine Fisher;William R. Gillespie;Matthew M. Riggs;Leonid Gibiansky;Marc R. Gastonguay
Affiliations:
Metrum Institute, Tariffville, CT, USA;Metrum Institute, Tariffville, CT, USA;Metrum Institute, Tariffville, CT, USA;Metrum Institute, Tariffville, CT, USA;Metrum Institute, Tariffville, CT, USA;QuantPharm LLC, North Potomac, MD, USA;Metrum Institute, Tariffville, CT, USA
Venue:
Computer Methods and Programs in Biomedicine
Year:
2013

Citing 4
Cited 1

The relational model for database management: version 2

The relational model for database management: version 2
WinBUGS – A Bayesian modelling framework: Concepts, structure, and extensibility

Statistics and Computing
NONMEMory: A run management tool for NONMEM

Computer Methods and Programs in Biomedicine
Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

Computer Methods and Programs in Biomedicine

Evaluating an online pharmaceutical education system for pharmacy interns in critical care settings

Computer Methods and Programs in Biomedicine

Quantified Score

Hi-index	0.00

Visualization

Abstract

metrumrg is an R package that facilitates workflow for the discipline of pharmacometrics. Support is provided for data preparation, modeling, simulation, diagnostics, and reporting. Existing tools and techniques are emphasized where available; original solutions are provided for otherwise unmet needs. In particular, metrumrg implements an R interface for the NONMEM^(R) modeling software, optionally run in a distributed computing environment. The paradigm allows start-to-finish analyses in a single scripting language. Emphasis on text-based formats promotes traceability of results.