Identification of risk factors for TRALI using a hybrid algorithm

  • Authors:
  • María Dolores Torres;Aurora Torres;Felipe Cuellar;María de la Luz Torres;Eunice Ponce de León;Francisco Pinales

  • Affiliations:
  • Universidad Autónoma de Aguascalientes, Aguascalientes, Ags, México;Universidad Autónoma de Aguascalientes, Aguascalientes, Ags, México;Centenario Hospital Miguel Hidalgo, Aguascalientes, Ags, México;Centenario Hospital Miguel Hidalgo, Aguascalientes, Ags, México;Universidad Autónoma de Aguascalientes, Aguascalientes, Ags, México;Universidad Autónoma de Aguascalientes, Aguascalientes, Ags, México

  • Venue:
  • MICAI'12 Proceedings of the 11th Mexican international conference on Advances in Artificial Intelligence - Volume Part I
  • Year:
  • 2012

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Abstract

This paper presents a hybrid evolutionary algorithm to identify risk factors associated with transfusion related acute lung injury (TRALI). This medical condition occurs mainly in intensive care units and operating rooms, and the main strategy for its treatment is prevention. The proposed algorithm works with information from the model known as "two hits", in which the first hit is the original disease and the second corresponds to the blood transfusion. This algorithm is based on a genetic algorithm hybridized with testor analysis. This research used information from 87 patients treated at the Centenary Hospital Miguel Hidalgo in the city of Aguascalientes, Mexico. As a result of the algorithm's application, it was found that most variables are related to the first hit, while only some of them belong to the second one. The analysis also revealed that some variables physicians believed significant a priori, were not very important; among other discoveries.