Advanced resource connector middleware for lightweight computational Grids
Future Generation Computer Systems - Special section: Information engineering and enterprise architecture in distributed computing environments
A Grid-Enabled Gateway for Biomedical Data Analysis
Journal of Grid Computing
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The steady increase of the biological data encourages computer scientists to develop data-analytical methods in order to study the biological systems. Most of these methods are firstly presented in the sequential version and then it is converted to a parallel version due to the constant expanding of data size. In this paper, we present a tool to eliminate the time gap between the two versions, sequential and parallel. The proposed tool acts as a middleware with a generic built in work-flow. The middleware manages a set of instances of the same sequential method; it manages to assign the data to each instance, to merge the results of all instances, and to form the final results. The proposed tool is applicable for problems with data decomposition nature (e.g., protein structure comparison, sequence comparison and CpG Islands search). It targets two levels of parallelism, which are the homogenous multi-core processor architectures and networks of heterogeneous computational nodes. The experimental results, of different computational biology problems, show a speedup close to the optimal with identical accuracy.