Sample-space-based feature extraction and class preserving projection for gene expression data

  • Authors:
  • Wenjun Wang

  • Affiliations:
  • School of Computer Science and Engineering, Xidian University, Post Box 161, #2 TaiBai Road, Xi'an, 710071, China

  • Venue:
  • International Journal of Data Mining and Bioinformatics
  • Year:
  • 2013

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Abstract

In order to overcome the problems of high computational complexity and serious matrix singularity for feature extraction using Principal Component Analysis PCA and Fisher's Linear Discrinimant Analysis LDA in high-dimensional data, sample-space-based feature extraction is presented, which transforms the computation procedure of feature extraction from gene space to sample space by representing the optimal transformation vector with the weighted sum of samples. The technique is used in the implementation of PCA, LDA, Class Preserving Projection CPP which is a new method for discriminant feature extraction proposed, and the experimental results on gene expression data demonstrate the effectiveness of the method.