Computational Aspects of Pathology Image Classification and Retrieval

  • Authors:
  • Arthur Wetzel

  • Affiliations:
  • Pittsburgh Supercomputing Center, 4400 Fifth Ave., Pittsburgh, PA 15213, USA Room 403, Mellon Institute, phone 412-268-3912 Fax 412-268-8532 awetzel@psc.edu

  • Venue:
  • The Journal of Supercomputing - Special issue on supercomputing in medicine
  • Year:
  • 1997

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Abstract

We are investigating the role of high performance computing for supportof a comprehensive pathology image atlas. The primary computing component isa database access mechanism providing retrieval by content based imagematching (CBIR) along with traditional term based queries. Anorganization based on information theoretic and Bayesian principles usingdecision trees and signature files is being developed. The essential role ofHPC is the discovery, selection, and optimization of medically useful imagefeature sets via genetic algorithm and simulated annealing methods. Thispaper outlines the problem area along with aspects of the underlyingtheoretical basis and distinguishing computing characteristics. Efficiencyof key portions of the computations can be greatly improved by usingparallelism within the computer word length using bit counting instructionsto implement voting and multimedia style instruction sets for low levelimage processing.