Oriented tensor reconstruction: tracing neural pathways from diffusion tensor MRI

  • Authors:
  • Leonid Zhukov;Alan H. Barr

  • Affiliations:
  • California Institute of Technology;California Institute of Technology

  • Venue:
  • Proceedings of the conference on Visualization '02
  • Year:
  • 2002

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Abstract

In this paper we develop a new technique for tracing anatomical fibers from 3D tensor fields. The technique extracts salient tensor features using a local regularization technique that allows the algorithm to cross noisy regions and bridge gaps in the data. We applied the method to human brain DT-MRI data and recovered identifiable anatomical structures that correspond to the white matter brain-fiber pathways. The images in this paper are derived from a dataset having 121x88x60 resolution. We were able to recover fibers with less than the voxel size resolution by applying the regularization technique, i.e., using a priori assumptions about fiber smoothness. The regularization procedure is done through a moving least squares filter directly incorporated in the tracing algorithm.