Incorporating an Image Distortion Model in Non-rigid Alignment of EPI with Conventional MRI

  • Authors:
  • Colin Studholme;R. Todd Constable;James S. Duncan

  • Affiliations:
  • -;-;-

  • Venue:
  • IPMI '99 Proceedings of the 16th International Conference on Information Processing in Medical Imaging
  • Year:
  • 1999

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Abstract

This paper addresses the problem of accurately mapping echo planar image (EPI) data acquired for functional MRI studies to conventional T1 weighted anatomical MRI. In particular here we examine the correction of spin echo image distortion resulting from magnetic field inhomogeneity. To do this we must account for both geometric and intensity distortions within the EPI data. This approach combines ideas on multi-modality registration criteria, non-rigid registration and models of geometric and intensity distortion in MR image formation. Specifically the relationship between the geometric and intensity distortion in spin echo EPI imaging is used to constrain the geometric correction estimate and replaces the arbitrary smoothing energy term in non-rigid registration.