Mapping DNA by stochastic relaxation
Advances in Applied Mathematics
Multiple solutions of DNA restriction mapping problems
Advances in Applied Mathematics
Mapping the genome: some combinatorial problems arising in molecular biology
STOC '93 Proceedings of the twenty-fifth annual ACM symposium on Theory of computing
Computers and Intractability: A Guide to the Theory of NP-Completeness
Computers and Intractability: A Guide to the Theory of NP-Completeness
Genetic algorithm for double digest problem
PReMI'05 Proceedings of the First international conference on Pattern Recognition and Machine Intelligence
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The double digest problem is a common NP-hard approach to constructing physical maps of DNA sequences. This paper presents a new approach called the enhanced double digest problem. Although this new problem is also NP-hard, it can be solved in linear time under a certain restriction, which is satisfied reasonably frequently.