Binary Vector of Real Value Coding for Secondary Structure Prediction? A Case Study of Polyproline Type II Prediction

  • Authors:
  • Markku Siermala;Martti Juhola;Mauno Vihinen

  • Affiliations:
  • -;-;-

  • Venue:
  • ISMDA '01 Proceedings of the Second International Symposium on Medical Data Analysis
  • Year:
  • 2001

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Abstract

Amino acid sequences are usually described using categorical variables which are difficult to change to a numerical form. We compare two numerical coding methods in polyproline type II secondary structure predictions, the frequently used binary vector coding method and our new real value coding method based on the PAM250 substitution table which consists of amino acid mutation information. The real value coding method has good properties such as space saving and illustrative form. Our first results are almost comparable to the results of traditional binary vector coding method.