CLASSIC: a structural data model for objects
SIGMOD '89 Proceedings of the 1989 ACM SIGMOD international conference on Management of data
PDM: an object-oriented data model
Readings in object-oriented database systems
Panel: scientific data management for human genome applications
Data Engineering
The ToolTalk service: an inter-operability solution
The ToolTalk service: an inter-operability solution
The human genome project and informatics
Communications of the ACM
SCENE—a computational interface system
Computers in Physics
An overview of the object protocol model (OPM) and the OPM data management tools
Information Systems - Special issue: databases: their creation, management and utilization
Computational proxies: an object-based infrastructure for computational science
Computational proxies: an object-based infrastructure for computational science
Fast discovery of association rules
Advances in knowledge discovery and data mining
Managing semantic heterogeneity in databases: a theoretical prospective
PODS '97 Proceedings of the sixteenth ACM SIGACT-SIGMOD-SIGART symposium on Principles of database systems
Proceedings of the Eighth International Conference on Scientific and Statistical Database Management
SSDBM '96 Proceedings of the Eighth International Conference on Scientific and Statistical Database Management
VLDB '84 Proceedings of the 10th International Conference on Very Large Data Bases
A Data Transformation System for Biological Data Sources
VLDB '95 Proceedings of the 21th International Conference on Very Large Data Bases
ZOO: A Desktop Experiment Management Environment
VLDB '96 Proceedings of the 22th International Conference on Very Large Data Bases
Computational Proxies: Modeling Scientific Applications in Object Databases
Proceedings of the Seventh International Working Conference on Scientific and Statistical Database Management
A Federated DBMS-Based Integrated Environment for Molecular Biology
Proceedings of the Seventh International Working Conference on Scientific and Statistical Database Management
Data Mining: Machine Learning, Statistics, and Databases
SSDBM '96 Proceedings of the Eighth International Conference on Scientific and Statistical Database Management
Using the Functional Data Model to Integrate Distributed Biological Data Sources
SSDBM '96 Proceedings of the Eighth International Conference on Scientific and Statistical Database Management
Programming Constructs for Unstructured Data
DBLP-5 Proceedings of the Fifth International Workshop on Database Programming Languages
Object-oriented database support for computational chemistry
SSDBM'1992 Proceedings of the 6th international working conference on Scientific and statistical database management
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Molecular biology applications, like those of other scientific domains, need to store and view large amounts of specialized quantitative information. With the advent of high speed sequencing technology and considerable funding to ``map" the genomes of key biological organisms, public databases such as GenBank, PDB, EMBL, JIPID, and SwissProt make millions of genetic sequences available to molecular biologists, and industry and university laboratories maintain large databases. The need for common interfaces and query languages to exploit these heterogeneous databases is well documented, and several such systems now exist or are under development. Our own work on database and program interoperability in this domain has shown, however, that providing an interface is but a first step towards making these databases fully useful.The system we are developing integrates and tracks inputs and results from numerous computational biology programs. It helps researchers organize result items from sequence comparisons into ``clusters" that can be marked, named, annotated, and manipulated. An alpha version is implemented in Smalltalk.This paper describes the scientific problem our system aims to solve, as well as current barriers to development and research opportunities suggested by those barriers. We present its conceptual data model, the current prototype, and future implementation plans.