Inverse Parametric Sequence Alignment

  • Authors:
  • Fangting Sun;David Fernández-Baca;Wei Yu

  • Affiliations:
  • -;-;-

  • Venue:
  • COCOON '02 Proceedings of the 8th Annual International Conference on Computing and Combinatorics
  • Year:
  • 2002

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Abstract

We consider the inverse parametric sequence alignment problem, where a sequence alignment is given and the task is to determine parameter values such that the given alignment is optimal at that parameter setting. We describe a O(mnlog n)-time algorithm for inverse global alignment without gap penalty and a O(mn logm) time algorithm for global alignment with gap penalty, where m, n (n = m) are the lengths of input strings. We then discuss algorithms for local alignment.