In Vivo Data Acquisition Instrument for Solid Organ Mechanical Property Measurement

Authors:
Mark P. Ottensmeyer;John Kenneth Salisbury, Jr.
Affiliations:
-;-
Venue:
MICCAI '01 Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention
Year:
2001

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Abstract

Surgical simulation systems need not only models that capture the behaviors of living tissue, but also parameters measured from real tissues to make such models meaningful. A portable system called the TeMPeST 1-D (Tissue Material Property Sampling Tool) that can acquire force-displacement responses in vivo has been developed. By fitting these data to the form of a chosen model, the tissue parameters can be obtained.The data acquisition tool is suitable for minimally invasive or open surgical use. It measures normal indentation force-displacement response over a frequency range from DC to approximately 100Hz. This permits the investigation of the visco-elastic properties of living solid organ tissue. It can exert forces up to 300 mN, and has a range of motion of 卤500碌m. The TeMPeST 1-D was used to measure the frequency-dependent stiffness of porcine liver in vivo in a proof-of-concept demonstration, and is being used in a more comprehensive series of tests. Based on simple tissue models, preliminary estimates for tissue stiffness are presented and the frequency-dependent and non-linear characteristics are discussed.