Fusion of Histological Sections and MR Images: Towards the Construction of an Atlas of the Human Basal Ganglia

  • Authors:
  • Sébastien Ourselin;Eric Bardinet;D. Dormont;Grégoire Malandain;Alexis Roche;Nicholas Ayache;D. Tandé;K. Parain;J. Yelnik

  • Affiliations:
  • -;-;-;-;-;-;-;-;-

  • Venue:
  • MICCAI '01 Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention
  • Year:
  • 2001

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Abstract

In neurosurgery, localisation of deep brain structures is a crucial issue, which can be assisted by a 3-dimensional brain atlases. Our goal is to build such an atlas by fusing histological data with a 3D MR image of the same subject. This requires two steps: first a 2D realignment of the histological sections in order to obtain a three-dimensional block, then a 3D registration between this reconstructed block and the MR image. Both steps are based on the same robust registration algorithm.