Incomplete Directed Perfect Phylogeny

  • Authors:
  • Itsik Pe'er;Ron Shamir;Roded Sharan

  • Affiliations:
  • -;-;-

  • Venue:
  • COM '00 Proceedings of the 11th Annual Symposium on Combinatorial Pattern Matching
  • Year:
  • 2000

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Abstract

Perfect phylogeny is one of the fundamental models for studying evolution. We investigate the following generalization of the problem: The input is a species-characters matrix. The characters are binary and directed, i.e., a species can only gain characters. The difference from standard perfect phylogeny is that for some species the state of some characters is unknown. The question is whether one can complete the missing states in a way admitting a perfect phylogeny. The problem arises in classical phylogenetic studies, when some states are missing or undetermined. Quite recently, studies that infer phylogenies using inserted repeat elements in DNA gave rise to the same problem. The best known algorithm for the problem requires O(n2m) time for m characters and n species. We provide a near optimal Õ(nm)-time algorithm for the problem.