Multiscale Modeling of Alternative Splicing Regulation

  • Authors:
  • Damien Eveillard;Delphine Ropers;Hidde de Jong;Christiane Branlant;Alexander Bockmayr

  • Affiliations:
  • -;-;-;-;-

  • Venue:
  • CMSB '03 Proceedings of the First International Workshop on Computational Methods in Systems Biology
  • Year:
  • 2003

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Abstract

Alternative splicing is a key process in post-transcriptional regulation, by which several kinds of mature RNA can be obtained from the same premessenger RNA. Using a constraint programming approach, we model the alternative splicing regulation at different scales (single site vs. multiple sites), thus exploiting different types of available experimental data.