Deduction of a gene regulatory relationship framework from gene expression data by the application of graphical Gaussian modeling

Authors:
Sachiyo Aburatani;Satoru Kuhara;Hiroyuki Toh;Katsuhisa Horimoto
Affiliations:
Laboratory of Molecular Gene Technics, Graduate School of Genetic Resources Technology, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan;Laboratory of Molecular Gene Technics, Graduate School of Genetic Resources Technology, Kyushu University, Hakozaki 6-10-1, Higashi-ku, Fukuoka 812-8581, Japan;Laboratory of Genome Informatics, Bioinformatics Center, Institute of Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan;Laboratory of Biostatistics, Human Genome Center, Institute of Medical Science, University of Tokyo, 4-6-1 Shirokane-dai, Minato-ku, Tokyo 108-8639, Japan
Venue:
Signal Processing - Special issue: Genomic signal processing
Year:
2003

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Abstract

Feature selection is problematic when the number of potential features is very large. Absent distribution knowledge, to select a best feature set of a certain size requires that all feature sets of that size be examined. This paper considers the question ...