Codeword design and information encoding in DNA ensembles
Natural Computing: an international journal
Development, evaluation and benchmarking of simulation software for biomolecule-based computing
Natural Computing: an international journal
Towards evolutionary DNA computing
IWINAC'05 Proceedings of the First international conference on Mechanisms, Symbols, and Models Underlying Cognition: interplay between natural and artificial computation - Volume Part I
Characterization of non-crosshybridizing DNA oligonucleotides manufactured In Vitro
DNA'04 Proceedings of the 10th international conference on DNA computing
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An attractive feature of DNA-based computers is the large number of possible sequences (4n) of a given length n with which to represent information. The problem, however, is that any given sequence is not necessarily independent of the other sequences, and thus, reactions among them can interfere with the reliability and efficiency of the computation. Independent sequences might be manufactured in the test tube using evolutionary methods. To this end, an in vitro selection has been developed that selects maximally mismatched DNA sequences. In order to understand the behavior of the protocol, a computer simulation of the protocol was done, results of which showed that Watson-Crick pairs of independent oligonucleotides were preferentially selected. In addition, to explore the computational capability of the selection protocol, a design is presented that generates the Fibonacci sequence of numbers.