Uses of Multiagents Systems for Simulation of MAPK Pathway

Authors:
Gabriel Querrec;Vincent Rodin;Jean François Abgrall;Sébastien Kerdelo;Jacques Tisseau
Affiliations:
-;-;-;-;-
Venue:
BIBE '03 Proceedings of the 3rd IEEE Symposium on BioInformatics and BioEngineering
Year:
2003

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Abstract

Since emergence of molecular biology, one has improved knowledge about intracellular network controlling cell behavior. In parallel, advances in mathematic and computer science allow to simulate such complex phenomena. Moreover, most methods need a global resolution of the system which makes it difficult to be created and modified. We proposed, in this study, a distributed approach by multi-agent system (MAS), to simulate MAPK pathway. Our results show that such simulation is possible and allows "in virtuo" experimentation, i.e. model perturbation during its execution.