A Literature Based Method for Identifying Gene-Disease Connections

  • Authors:
  • Lada A. Adamic;Dennis Wilkinson;Bernardo A. Huberman;Eytan Adar

  • Affiliations:
  • -;-;-;-

  • Venue:
  • CSB '02 Proceedings of the IEEE Computer Society Conference on Bioinformatics
  • Year:
  • 2002

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Abstract

We present a statistical method that can swiftly identify, from the literature, sets of genes known to be associated with given diseases. It offers a comprehensive way to treat alias symbols, a statistical method for computing the relevance of the gene to the query, and a novel way to disambiguate gene symbols from other abbreviations. The method is illustrated by finding genes related to breast cancer.