Multiresolution elastic matching
Computer Vision, Graphics, and Image Processing
Matching 3-D anatomical surfaces with non-rigid deformations using octree-splines
International Journal of Computer Vision
Alignment by maximization of mutual information
ICCV '95 Proceedings of the Fifth International Conference on Computer Vision
Deformable templates using large deformation kinematics
IEEE Transactions on Image Processing
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We study an application of image registration in the medical domain. Based on a 3-D hierarchical deformable registration algorithm, we have developed a prototype system which automatically aligns a standard atlas to a subject's data to create a customized atlas. Combined with domain knowledge, the registration algorithm can also detect asymmetries and abnormal variations in the subject's data that indicate the existence and location of pathologies. We have conducted tests on 106 MRI scans of normal brains, 3 MRI and I CT scan of brains with pathologies, with results qualitatively comparable to manual segmentation.