Federated database systems for managing distributed, heterogeneous, and autonomous databases
ACM Computing Surveys (CSUR) - Special issue on heterogeneous databases
Logical foundations of object-oriented and frame-based languages
Journal of the ACM (JACM)
Object-oriented multidatabase systems: a solution for advanced applications
Object-oriented multidatabase systems: a solution for advanced applications
Your mediators need data conversion!
SIGMOD '98 Proceedings of the 1998 ACM SIGMOD international conference on Management of data
Issues and approaches of database integration
Communications of the ACM
A layered architecture for querying dynamic Web content
SIGMOD '99 Proceedings of the 1999 ACM SIGMOD international conference on Management of data
Managing semistructured data with florid: a deductive object-oriented perspective
Information Systems - Special issue on semistructured data
Context interchange: new features and formalisms for the intelligent integration of information
ACM Transactions on Information Systems (TOIS)
Navigation-Driven Evaluation of Virtual Mediated Views
EDBT '00 Proceedings of the 7th International Conference on Extending Database Technology: Advances in Database Technology
WOL: A Language for Database Transformations and Constraints
ICDE '97 Proceedings of the Thirteenth International Conference on Data Engineering
ICDT '97 Proceedings of the 6th International Conference on Database Theory
Ontological Foundations for Biology Knowledge Models
Proceedings of the Fourth International Conference on Intelligent Systems for Molecular Biology
ISMIS '94 Proceedings of the 8th International Symposium on Methodologies for Intelligent Systems
Information Integration: Conceptual Modeling and Reasoning Support
COOPIS '98 Proceedings of the 3rd IFCIS International Conference on Cooperative Information Systems
Ontobroker: Ontology Based Access to Distributed and Semi-Structured Information
DS-8 Proceedings of the IFIP TC2/WG2.6 Eighth Working Conference on Database Semantics- Semantic Issues in Multimedia Systems
A Unified Framework for Wrapping, Mediating and Restructuring Information from the Web
ER '99 Proceedings of the Workshops on Evolution and Change in Data Management, Reverse Engineering in Information Systems, and the World Wide Web and Conceptual Modeling
Semantic and schematic similarities between database objects: a context-based approach
The VLDB Journal — The International Journal on Very Large Data Bases
Model-Based Information Integration in a Neuroscience Mediator System
VLDB '00 Proceedings of the 26th International Conference on Very Large Data Bases
A System for Managing Alternate Models in Model-Based Mediation
BNCOD 19 Proceedings of the 19th British National Conference on Databases: Advances in Databases
On the Semantics of Anonymous Identity and Reification
On the Move to Meaningful Internet Systems, 2002 - DOA/CoopIS/ODBASE 2002 Confederated International Conferences DOA, CoopIS and ODBASE 2002
Well-Founded Optimism: Inheritance in Frame-Based Knowledge Bases
On the Move to Meaningful Internet Systems, 2002 - DOA/CoopIS/ODBASE 2002 Confederated International Conferences DOA, CoopIS and ODBASE 2002
A Metadata Integration Assistant Generator for Heterogeneous Distributed Databases
On the Move to Meaningful Internet Systems, 2002 - DOA/CoopIS/ODBASE 2002 Confederated International Conferences DOA, CoopIS and ODBASE 2002
Registering Scientific Information Sources for Semantic Mediation
ER '02 Proceedings of the 21st International Conference on Conceptual Modeling
FLORA: Implementing an Efficient DOOD System Using a Tabling Logic Engine
CL '00 Proceedings of the First International Conference on Computational Logic
Towards a formalization of disease-specific ontologies for neuroinformatics
Neural Networks - Special issue: Neuroinformatics
Proceedings of the 2004 ACM symposium on Applied computing
Integration of biological sources: current systems and challenges ahead
ACM SIGMOD Record
A Collaborative Informatics Infrastructure for Multi-Scale Science
Cluster Computing
Semantic enrichment for medical ontologies
Journal of Biomedical Informatics
Bio-Broker: a tool for integration of biological data sources and data analysis tools
Software—Practice & Experience
Journal of Intelligent Information Systems
A pragmatic approach to mapping the open biomedical ontologies
International Journal of Bioinformatics Research and Applications
A metadata tool for retrieval from heterogeneous distributed XML documents
ICCS'03 Proceedings of the 2003 international conference on Computational science
Editorial: BioDB: An ontology-enhanced information system for heterogeneous biological information
Data & Knowledge Engineering
Bioinformatics data source integration based on semantic relationships across species
VDMB'06 Proceedings of the First international conference on Data Mining and Bioinformatics
Learning layouts of biological datasets semi-automatically
DILS'05 Proceedings of the Second international conference on Data Integration in the Life Sciences
Data integration in the biomedical informatics research network (BIRN)
DILS'05 Proceedings of the Second international conference on Data Integration in the Life Sciences
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The need for information integration is paramount in many biological disciplines, because of the large heterogeneity in both the types of data involved and in the diversity of approaches (physiological, anatomical, biochemical, etc.) taken by biologists to study the same or correlated phenomena. However, the very heterogeneity makes the task of information integration very difficult since two approaches studying different aspects of the same phenomena may not even share common attributes in their schema description. This paper develops a wrapper-mediator architecture, which extends the conventional data- and view-oriented information mediation approach by incorporating additional knowledge-modules that bridge the gap between the heterogeneous data sources. The semantic integration of the disparate local data sources employs F-logic as a data and knowledge representation and reasoning formalism. We show that the rich object-oriented modeling features of F-logic together with its declarative rule language and the uniform treatment of data and metadata (schema information) make it an ideal candidate for complex integration tasks. We substantiate this claim by elaborating on our integration architecture and illustrating the approach using real world examples from the neuroscience domain. The complete integration framework is currently under development; a first prototype establishing the viability of the approach is operational.