Adaptation in natural and artificial systems
Adaptation in natural and artificial systems
Protein Architecture: A Practical Approach
Protein Architecture: A Practical Approach
Genetic Algorithms in Search, Optimization and Machine Learning
Genetic Algorithms in Search, Optimization and Machine Learning
Genetic Algorithms for Protein Tertiary Structure Prediction
ECML '93 Proceedings of the European Conference on Machine Learning
Application of Genetic Algorithms in Chemometrics
Proceedings of the 3rd International Conference on Genetic Algorithms
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This chapter demonstrates the application of genetic algorithms to the ab initio protein folding problem. In particular, solutions to the representation issue of protein tertiary structure, of domain-specific genetic operators and a vector fitness function for fold evaluation are presented. Finally, limitations of this approach are discussed.