Computer visualization of long genomic sequences

  • Authors:
  • Dachywan Wu;James Robergé;Douglas J. Cork;Bao Gia Nguyen;Thom Grace

  • Affiliations:
  • Illinois Institute of Technology, Chicago, IL;Illinois Institute of Technology, Chicago, IL;Illinois Institute of Technology, Chicago, IL;Illinois Institute of Technology, Chicago, IL;Illinois Institute of Technology, Chicago, IL

  • Venue:
  • VIS '93 Proceedings of the 4th conference on Visualization '93
  • Year:
  • 1993

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Abstract

Human beings find it difficult to analyze local and global oligonucleotide patterns in the linear primary sequences of a genome. In this paper, we present a family of iterated function systems (IFS) that can be used to generate a set of visual models of a DNA sequence. A new visualization function, the W-curve, that is derived from this IFS family is introduced. Using W-curves, a user can readily compare subsequences within a long genomic sequence --- or between genomic sequences --- and can visually evaluate the effect of local variations (mutations) upon the global genomic information content.