CLUSTAG: hierarchical clustering and graph methods for selecting tag SNPs

  • Authors:
  • S. I. Ao;Kevin Yip;Michael Ng;David Cheung;Pui-Yee Fong;Ian Melhado;Pak C. Sham

  • Affiliations:
  • Department of Mathematics, The University of Hong Kong Pokfulam, Hong Kong;Department of Computer Science, The University of Hong Kong Pokfulam, Hong Kong;Department of Mathematics, The University of Hong Kong Pokfulam, Hong Kong;Department of Computer Science, The University of Hong Kong Pokfulam, Hong Kong;Genome Research Center, The University of Hong Kong Pokfulam, Hong Kong;Genome Research Center, The University of Hong Kong Pokfulam, Hong Kong;Genome Research Center, The University of Hong Kong Pokfulam, Hong Kong

  • Venue:
  • Bioinformatics
  • Year:
  • 2005

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Abstract

Summary: Cluster and set-cover algorithms are developed to obtain a set of tag single nucleotide polymorphisms (SNPs) that can represent all the known SNPs in a chromosomal region, subject to the constraint that all SNPs must have a squared correlation R2 C with at least one tag SNP, where C is specified by the user. Availability: http://hkumath.hku.hk/web/link/CLUSTAG/CLUSTAG.html Contact: mng@maths.hku.hk