A Dynamic Workflow Approach for the Integration of Bioinformatics Services

Authors:
Malika Mahoui;Lingma Lu;Ning Gao;Nianhua Li;Jessica Chen;Omran Bukhres;Zina Ben Miled
Affiliations:
School of Informatics, IUPUI, Indianapolis, USA 4620;Department of Computer and Information Science, IUPUI, USA;Department of Electrical and Computer Engineering, IUPUI, USA;Department of Electrical and Computer Engineering, IUPUI, USA;School of Informatics, IUPUI, Indianapolis, USA 4620;Department of Computer and Information Science, IUPUI, USA;Department of Electrical and Computer Engineering, IUPUI, USA
Venue:
Cluster Computing
Year:
2005

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Abstract

Modern biological and chemical studies rely on life science databases as well as sophisticated software tools (e.g., homology search tools, modeling and visualization tools). These tools often have to be combined and integrated in order to support a given study. SIBIOS (System for the Integration of Bioinformatics Services) serves this purpose. The services are both life science database search services and software tools. The task engine is the core component of SIBIOS. It supports the execution of dynamic workflows that incorporate multiple bioinformatics services. The architecture of SIBIOS, the approaches to addressing the heterogeneity as well as interoperability of bioinformatics services, including data integration are presented in this paper.