Algorithmic self-assembly of dna
Algorithmic self-assembly of dna
Computer-aided design for DNA self-assembly: process and applications
ICCAD '05 Proceedings of the 2005 IEEE/ACM International conference on Computer-aided design
Using CAD to shape experiments in molecular QCA
Proceedings of the 2006 IEEE/ACM international conference on Computer-aided design
Molecular QCA design with chemically reasonable constraints
ACM Journal on Emerging Technologies in Computing Systems (JETC)
Nondeterministic polynomial time factoring in the tile assembly model
Theoretical Computer Science
Solving NP-complete problems in the tile assembly model
Theoretical Computer Science
Toward minimum size self-assembled counters
Natural Computing: an international journal
Solving satisfiability in the tile assembly model with a constant-size tileset
Journal of Algorithms
Pictures worth a thousand tiles, a geometrical programming language for self-assembly
Theoretical Computer Science
Toward minimum size self-assembled counters
DNA13'07 Proceedings of the 13th international conference on DNA computing
DNA origami as self-assembling circuit boards
UC'10 Proceedings of the 9th international conference on Unconventional computation
Programming and evolving physical self-assembling systems in three dimensions
Natural Computing: an international journal
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The generation of arbitrary patterns and shapes at very small scales is at the heart of our effort to miniaturize circuits and is fundamental to the development of nanotechnology. Here I review a recently developed method for folding long single strands of DNA into arbitrary two-dimensional shapes using a raster fill technique - 'scaffolded DNA origami'. Shapes up to 100 nanometers in diameter can be approximated with a resolution of 6 nanometers and decorated with patterns of roughly 200 binary pixels at the same resolution. Experimentally verified by the creation of a dozen shapes and patterns, the method is easy, high yield, and lends itself well to automated design and manufacture. So far, CAD tools for scaffolded DNA origami are simple, require hand-design of the folding path, and are restricted to two dimensional designs. If the method gains wide acceptance, better CAD tools will be required.