DNASequencesGenerator: A Program for the Construction of DNA Sequences
DNA 7 Revised Papers from the 7th International Workshop on DNA-Based Computers: DNA Computing
Optimization of supply diversity for the self-assembly of simple objects in two and three dimensions
Natural Computing: an international journal
Design and simulation of self-repairing DNA lattices
DNA'06 Proceedings of the 12th international conference on DNA Computing
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DNA self-assembly is an emerging technology with potential as a future replacement of conventional lithographic fabrication. A key challenge is the specification of appropriate DNA sequences that are optimal according to specified metrics and satisfy various design rules. To meet this challenge we developed a thermodynamics-based design automation tool to evaluate the vast DNA sequence space (2.8k base pairs) and select appropriate sequences. We use this tool to design DNA nanostructures that were previously impossible with existing text distance based tools. We also show that for nanoscale structures our approach produces superior results compared to existing tools.