An efficient algorithm to detect palindromes in DNA sequences using periodicity transform

  • Authors:
  • Ravi Gupta;Ankush Mittal;Sumit Gupta

  • Affiliations:
  • Department of Electronics and Computer Engineering, Indian Institute of Technology, Roorkee, Uttaranchal, India;Department of Electronics and Computer Engineering, Indian Institute of Technology, Roorkee, Uttaranchal, India;Department of Electronics and Computer Engineering, Indian Institute of Technology, Roorkee, Uttaranchal, India

  • Venue:
  • Signal Processing - Special section: Advances in signal processing-assisted cross-layer designs
  • Year:
  • 2006

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Abstract

This paper presents an algorithm to detect exact and inexact palindromes of a given size in DNA sequences by applying signal processing techniques. The algorithm uses modified periodicity transform to calculate compensated periodogram coefficient, which acts as a correlation parameter for detection of inexact palindromes. Detailed experiments conducted on a number of synthetic and actual DNA sequences show efficiency and accuracy of our method for detecting inexact palindromes. A comparison between our method and the standard technique shows that the increase in execution time with large sample size is significantly less in our method as compared to the standard technique.