Using a fuzzy framework for delineation and decomposition of Immunoglobulin G in cryo electron tomographic images

Authors:
Stina Svensson;Magnus Gedda;Duccio Fanelli;Ulf Skoglund;Lars-Goran Ofverstedt;Sara Sandin
Affiliations:
Swedish University of Agricultural Sciences and Uppsala University;Swedish University of Agricultural Sciences and Uppsala University;Karolinska Institutet, Stockholm, Sweden;Karolinska Institutet, Stockholm, Sweden;Karolinska Institutet, Stockholm, Sweden;MRC Laboratory of Molecular Biology, Cambridge, UK
Venue:
ICPR '06 Proceedings of the 18th International Conference on Pattern Recognition - Volume 04
Year:
2006

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Abstract

In structural studies of proteins, the first task is to identify the different parts of the protein. We present a robust method using a fuzzy framework for delineating a protein and to identify its parts. The method is used in a study of the immunoglobulin G antibody, individually imaged using cryo electron tomography, with satisfactory results.