Global Similarity and Local Variance in Human Gene Coexpression Networks
AICI '09 Proceedings of the International Conference on Artificial Intelligence and Computational Intelligence
An integrated model for visualizing biclusters from gene expression data and PPI networks
ISB '10 Proceedings of the International Symposium on Biocomputing
| Hi-index | 3.84 |
Motivation: Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community. Results: We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules. Availability: The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca contact: shuyepu@sickkids.ca