A high performance grid-web service framework for the identification of 'conserved sequence tags'

  • Authors:

  • Paolo D'Onorio De Meo;Danilo Carrabino;Nico Sanna;Tiziana Castrignano;Giorgio Grillo;Flavio Licciulli;Sabino Liuni;Matteo Re;Flavio Mignone;Graziano Pesole

  • Affiliations:

  • CASPUR: Supercomputing Center for University and Research, Via dei Tizii, 6/b - 00185 Rome, Italy;CASPUR: Supercomputing Center for University and Research, Via dei Tizii, 6/b - 00185 Rome, Italy;CASPUR: Supercomputing Center for University and Research, Via dei Tizii, 6/b - 00185 Rome, Italy;CASPUR: Supercomputing Center for University and Research, Via dei Tizii, 6/b - 00185 Rome, Italy;Istituto Tecnologie Biomediche - Sezione di Bari, C.N.R., Bari, Italy;Istituto Tecnologie Biomediche - Sezione di Bari, C.N.R., Bari, Italy;Istituto Tecnologie Biomediche - Sezione di Bari, C.N.R., Bari, Italy;University of Milan, Dipartimento di Scienze Biomolecolari e Biotecnologie, via Celoria 26, Milan 20133, Italy;University of Milan, Dipartimento di Scienze Biomolecolari e Biotecnologie, via Celoria 26, Milan 20133, Italy;Istituto Tecnologie Biomediche - Sezione di Bari, C.N.R., Bari, Italy and University of Milan, Dipartimento di Scienze Biomolecolari e Biotecnologie, via Celoria 26, Milan 20133, Italy

  • Venue:
  • Future Generation Computer Systems
  • Year:
  • 2007

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Abstract

The continuous increasing of computing power in biological research places a threshold to the single host use and suggests an approach based on distributed computing. An emerging solution is grid technology, which allows organization to make better use of existing computing resources by providing them with a single, transparent, aggregated source of computing power. Equally, bioinformatics analysis often involves many web services, allowing shared access to information and helping the biologist to design, describe, record complex experiments. A new generation of grid infrastructure, where web services are building blocks, allow managent of a web services workflow. This work shows a tool for the identification and functional annotation of 'Conserved Sequence Tags' (CSTs) through cross-species genome comparisons, deployed on a Grid System Architecture, based on Web Services concepts and technologies.