Unified methodology of neural analysis in decision support systems built for pharmaceutical technology

Authors:
Aleksander Mendyk;Renata Jachowicz
Affiliations:
Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Collegium Medicum, Jagiellonian University, Kraków, Medyczna 9 St., 30-688 Kraków, Poland;Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Collegium Medicum, Jagiellonian University, Kraków, Medyczna 9 St., 30-688 Kraków, Poland
Venue:
Expert Systems with Applications: An International Journal
Year:
2007

Citing 3
Cited 0

Introduction to artificial neural systems

Introduction to artificial neural systems
Neural network as a decision support system in the development of pharmaceutical formulation-focus on solid dispersions

Expert Systems with Applications: An International Journal
Predicting drug dissolution profiles with an ensemble of boosted neural networks: a time series approach

IEEE Transactions on Neural Networks

Quantified Score

Hi-index	12.05

Visualization

Abstract

The objective of this study was to create universal methodology of artificial neural networks (ANNs) application in construction of decision support systems designed for various dosage forms. Two different dosage forms (solid dispersions and microemulsions) were modeled with use of the same methodology, software and hardware environments. Completely different models prepared confirmed their generalization ability both for solid dosage forms (solid dispersions) and liquid dosage forms (microemulsions). ME_expert and SD_expert systems basing on the neural expert committees were created. In the pilot study their application allowed for appropriate choice of qualitative and quantitative composition of particular pharmaceutical formulation. It was also proposed that ME_expert and SD_expert might provide in silico formulation procedures. Unified methodology of neural modeling in pharmaceutical technology was confirmed to be effective in providing valuable tools for pharmaceutical product development.