SMotif: a server for structural motifs in proteins

  • Authors:

  • Ganesan Pugalenthi;P. N. Suganthan;R. Sowdhamini;Saikat Chakrabarti

  • Affiliations:

  • School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798,;School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798,;School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798,;School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798,

  • Venue:
  • Bioinformatics
  • Year:
  • 2007

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Abstract

Summary: SMotif is a server that identifies important structural segments or motifs for a given protein structure(s) based on conservation of both sequential as well as important structural features such as solvent inaccessibility, secondary structural content, hydrogen bonding pattern and residue packing. This server also provides three-dimensional orientation patterns of the identified motifs in terms of inter-motif distances and torsion angles. These motifs may form the common core and therefore, can also be employed to design and rationalize protein engineering and folding experiments. Availability: SMotif server is available via the URL http://caps.ncbs.res.in/SMotif/index.html. Contact:chakraba@mail.nih.gov, mini@ncbs.res.in or EPNSugan@ntu.edu.sg Supplementary information: Supplementary data are available at Bioinformatics online.