Dynamic performance of accommodating intraocular lenses in a negative feedback control system: A simulation-based study

Authors:
Clifton M. Schor;Shrikant R. Bharadwaj;Christopher D. Burns
Affiliations:
Vision Science group, School of Optometry, University of California at Berkeley, Berkeley, CA 94720-2020, USA;Vision Science group, School of Optometry, University of California at Berkeley, Berkeley, CA 94720-2020, USA;Vision Science group, School of Optometry, University of California at Berkeley, Berkeley, CA 94720-2020, USA
Venue:
Computers in Biology and Medicine
Year:
2007

Citing 1
Cited 0

Multiple paired forward and inverse models for motor control

Neural Networks - Special issue on neural control and robotics: biology and technology

Quantified Score

Hi-index	0.00

Visualization

Abstract

A dynamic model of ocular accommodation is used to simulate the stability and dynamic performance of accommodating intraocular lenses (A-IOLs) that replace the hardened natural ocular lens that is unable to change focus. Accommodation simulations of an older eye with A-IOL materials having biomechanical properties of a younger eye illustrate overshoots and oscillations resulting from decreased visco-elasticity of the A-IOL. Stable dynamics of an A-IOL are restored by adaptation of phasic and tonic neural-control properties of accommodation. Simulations indicate that neural control must be recalibrated to avoid unstable dynamic accommodation with A-IOLs. An interactive web-model of A-IOL illustrating these properties is available at http://schorlab.berkeley.edu.