Neural Computation
Prediction with Gaussian processes: from linear regression to linear prediction and beyond
Learning in graphical models
Advanced lectures on machine learning
Population Pharmacokinetic and Dynamic Models: Parametric (P) and Nonparametric (NP) Approaches
CBMS '01 Proceedings of the Fourteenth IEEE Symposium on Computer-Based Medical Systems
An Adaptive Grid Non-Parametric Approach to Pharmacokinetic and Dynamic (PK/PD) Population Models
CBMS '01 Proceedings of the Fourteenth IEEE Symposium on Computer-Based Medical Systems
Brief Optimal trajectory planning and smoothing splines
Automatica (Journal of IFAC)
Regularization networks: fast weight calculation via Kalman filtering
IEEE Transactions on Neural Networks
Wavelet estimation by Bayesian thresholding and model selection
Automatica (Journal of IFAC)
Convex multi-task feature learning
Machine Learning
Brief paper: Fast algorithms for nonparametric population modeling of large data sets
Automatica (Journal of IFAC)
A new kernel-based approach for linear system identification
Automatica (Journal of IFAC)
Prediction error identification of linear systems: A nonparametric Gaussian regression approach
Automatica (Journal of IFAC)
A multi-task learning approach for the extraction of single-trial evoked potentials
Computer Methods and Programs in Biomedicine
Learning output kernels for multi-task problems
Neurocomputing
Hi-index | 22.15 |
Population models are used to describe the dynamics of different subjects belonging to a population and play an important role in drug pharmacokinetics. A nonparametric identification scheme is proposed in which both the average impulse response of the population and the individual ones are modelled as Gaussian stochastic processes. Assuming that the average curve is an integrated Wiener process, it is shown that its estimate is a cubic spline. An empirical Bayes algorithm for estimating both the average and the individual curves is worked out. The model is tested on simulated data sets as well as on xenobiotics pharmacokinetic data.