Introduction to statistical pattern recognition (2nd ed.)
Introduction to statistical pattern recognition (2nd ed.)
Topographic distance and watershed lines
Signal Processing - Special issue on mathematical morphology and its applications to signal processing
Self-organizing maps
IEEE Transactions on Pattern Analysis and Machine Intelligence
Pattern Classification (2nd Edition)
Pattern Classification (2nd Edition)
Augmented cell-graphs for automated cancer diagnosis
Bioinformatics
Modeling of remote sensing image content using attributed relational graphs
SSPR'06/SPR'06 Proceedings of the 2006 joint IAPR international conference on Structural, Syntactic, and Statistical Pattern Recognition
Histological image retrieval based on semantic content analysis
IEEE Transactions on Information Technology in Biomedicine
Perceptually uniform color spaces for color texture analysis: an empirical evaluation
IEEE Transactions on Image Processing
Computer Methods and Programs in Biomedicine
CIBCB'09 Proceedings of the 6th Annual IEEE conference on Computational Intelligence in Bioinformatics and Computational Biology
ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
Automatic classification of lymphoma images with transform-based global features
IEEE Transactions on Information Technology in Biomedicine
Improving the performance of k-means for color quantization
Image and Vision Computing
Pattern recognition in histopathological images: an ICPR 2010 contest
ICPR'10 Proceedings of the 20th International conference on Recognizing patterns in signals, speech, images, and videos
Counting lymphocytes in histopathology images using connected components
ICPR'10 Proceedings of the 20th International conference on Recognizing patterns in signals, speech, images, and videos
Content-based histopathology image retrieval using a kernel-based semantic annotation framework
Journal of Biomedical Informatics
CAIP'11 Proceedings of the 14th international conference on Computer analysis of images and patterns - Volume Part I
Color quantization using modified artificial fish swarm algorithm
AI'11 Proceedings of the 24th international conference on Advances in Artificial Intelligence
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Follicular lymphoma (FL) is a cancer of lymph system and it is the second most common lymphoid malignancy in the western world. Currently, the risk stratification of FL relies on histological grading method, where pathologists evaluate hematoxilin and eosin (H&E) stained tissue sections under a microscope as recommended by the World Health Organization. This manual method requires intensive labor in nature. Due to the sampling bias, it also suffers from inter- and intra-reader variability and poor reproducibility. We are developing a computer-assisted system to provide quantitative assessment of FL images for more consistent evaluation of FL. In this study, we proposed a statistical framework to classify FL images based on their histological grades. We introduced model-based intermediate representation (MBIR) of cytological components that enables higher level semantic description of tissue characteristics. Moreover, we introduced a novel color-texture analysis approach that combines the MBIR with low level texture features, which capture tissue characteristics at pixel level. Experimental results on real follicular lymphoma images demonstrate that the combined feature space improved the accuracy of the system significantly. The implemented system can identify the most aggressive FL (grade III) with 98.9% sensitivity and 98.7% specificity and the overall classification accuracy of the system is 85.5%.