Computing Reachable States for Nonlinear Biological Models

  • Authors:
  • Thao Dang;Colas Guernic;Oded Maler

  • Affiliations:
  • CNRS-VERIMAG, Gieres, France 38610;CNRS-VERIMAG, Gieres, France 38610;CNRS-VERIMAG, Gieres, France 38610

  • Venue:
  • CMSB '09 Proceedings of the 7th International Conference on Computational Methods in Systems Biology
  • Year:
  • 2009

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Abstract

In this paper we describe reachability computation for continuous and hybrid systems and its potential contribution to the process of building and debugging biological models. We then develop a novel algorithm for computing reachable states for nonlinear systems and report experimental results obtained using a prototype implementation. We believe these results constitute a promising contribution to the analysis of complex models of biological systems.